Ayush Aggarwal
PhD Student
CSIR-IGIB


PhD student in Biological Sciences working with Dr Vivek T. Natarajan at CSIR - IGIB, Delhi, India in the field of skin pigmentation and focusing on melanocyte biology. My PhD project involves understanding the melanocyte cell state/lineage transitions using a mix of computational and experimental approaches. Learn More.

Skilled in computational as well as experimental biology techniques

Want to see how your favourite gene behaves across multiple melanoycte developmetal and functional states? Check out MelDat a shiny web application I developed to quickly explore melanocyte related (bulk and single-cell) datasets. You can even visualize your own RNA seq or microarray datasets and create publication quality figures.

Publications

Aggarwal, A., Nasreen, A., Sahoo, S., Faruq, M., Pandey, R., Jolly, M.K., Singh, A., Gokhale, R.S., Natarajan, V.T., 2023. Melanocytes Exhibit Distinct Cell States Governed by A Gene Regulatory Network Under Stochastic Influence. (in communication)

Subramaniam, Y., Sharma, B., Aggarwal, A., Raja, D.A., Gupta, I., Ghazi, M., Sivasubbu, S. & Natarajan, V.T., 2023. Migration and establishment of progenitor pool of melanocytes is governed by SEMA3E-PLXND1 signaling. (under review at JCS)

Sultan, F., Basu, R., Murthy, D., Kochar, M., Attri, K.S., Aggarwal A., Kumari, P., Dnyane, P., Tanwar J., Motiani R.K., Singh, A., Gadgil, C., Bhavesh, N.S., Singh, P.K., Natarajan, V.T., Gokhale, R.S., 2022. Temporal analysis of melanogenesis identifies fatty acid metabolism as key skin pigment regulator. PLoS Biol. 20(5): e3001634.

Sharma, B., Subramaniam, Y.J., Raja, D.A., Aggarwal A., Sivasubbu, S., Natarajan, V.T., 2022. Reverse Genetic Approach to Identify Regulators of Pigmentation using Zebrafish. JoVE J. Vis. Exp.. e62955.

Dhawan, U.K., Bhattacharya, P., Narayanan, S., Manickam, V., Aggarwal A., Subramanian, M., 2021. Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression. Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 2598–2615.

Oh S, Abdelnabi J, Al-Dulaimi R, Aggarwal A, Ramos M, Davis S, Riester M, Waldron L, 2020. HGNChelper: identification and correction of invalid gene symbols for human and mouse [version 1; peer review: 2 approved, 1 approved with reservations]. F1000Research. 9:1493.

Raja, D.A., Subramaniam, Y.J., Aggarwal, A., Gotherwal, V., Babu, A., Tanwar, J., Motiani, R.K., Sivasubbu, S., Gokhale, R.S., Natarajan, V.T., 2020. Histone variant dictates fate biasing of neural crest cells to melanocyte lineage. Development.

Grover, R., Burse, S.A., Shankrit, S., Aggarwal, A., Kirty, K., Narta, K., Srivastav, R., Ray, A.K., Malik, G., Vats, A., Motiani, R.K., Thukral, L., Roy, S.S., Bhattacharya, S., Sharma, R., Natarajan, K., Mukerji, M., Pandey, R., Gokhale, R.S., Natarajan, V.T., 2019. Myg1 exonuclease couples the nuclear and mitochondrial translational programs through RNA processing. Nucleic Acids Res. 47, 5852–5866.